… protein Rai is a negative regulator of T cell receptor signaling … hyperactive phenotype of T
cells in autoimmune diseases. … suppresses TCR signaling and T cell activation, together with …

… negative regulators of G protein function and RhoG. ARHGDIG or Rho-GDP-dissociation
inhibitor-3 inhibits … against immunological disorders such as autoimmune diseases and other …

… activity of Rai as a negative regulator of TCR and BCR signaling, it has been observed that
… differentiation and autoimmunity The ability of Rai to fine-tune the antigen receptor signaling …

… B cell activation and the aberrant signaling downstream of … A diverse antigen receptor
repertoire is generated by the unique … It is established that PTPN22 is a negative regulator of SRC-…

… We have previously shown in the experimental autoimmune … that negatively regulates T cell
activation and Th17 cell … /TLR signaling pathway, the negative regulation of HIF-1α function, …

… + T lymphocytes and serve as negative regulators of inflammation … autoimmune process,
with a high recurrence rate after withdrawal. Alternative treatments are radioactive iodine (RAI) …

… The negative regulation of these early signals is key to avoid … clonally distributed antigen
receptor called the T-cell receptor (… of such signaling pathways is crucial to prevent autoimmune …

… against self-antigens and prevent autoimmunity. One … PD-1 in inhibiting T cell antigen
receptor (TCR) signaling, yet via distinct … Given the negative regulation of CD8 T cells by an LPA-…

… or IL-17 also they skewed autoimmune response. The up and … pathways involved in T-cell
activation and how aging alters … cancer cell growth using immune checkpoint inhibitors. Few …

… conditions like autoimmunity and infectious disease. … P2Y6 as a negative regulator of NK
cell maturation and function [80]. Among … In addition, the T cell activation via P2X7R inhibits the …